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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(3): 291-298
DOI: https://doi.org/10.20546/ijcmas.2019.803.036


Antibiotic Susceptibility Pattern in Clinical Isolates of Pseudomonas aeruginosa from a Tertiary Care Hospital of Tripura
Jayanta Debnath1, Anup Saha1*, Pradip Kumar Das1, Niladri Sekhar Das1 and Soma Saha2
1Department of Microbiology,
2Department of Medicine, Tripura Medical College & Dr. B.R. Ambedkar Memorial Teaching Hospital, Agartala, Tripura, India
*Corresponding author
Abstract:

Pseudomonas aeruginosa are established pathogens predominantly in various nosocomial infections which are often life threatening due to limited therapeutic options. The present study was undertaken to analyze the antibiotic susceptibility pattern in the clinical isolates of Pseudomonas aeruginosa, so as to establish the current therapeutic options available for treatment in this geographical area of North East India. The study was conducted on 150 strains of Pseudomonas aeruginosa isolated from various clinical samples. Isolation and confirmation of the organism in culture was performed using standard microbiological techniques. The antibiotic susceptibility testing was performed by Kirby Bauer Disc diffusion method. Out of all clinical samples 6.6% were identified to be Pseudomonas aeruginosa and 69.4% were elderly male patients. The highest numbers (62.7%) of isolates were from pulmonary samples like sputum, Endotracheal aspirate and Bronchoalveolar lavage, followed by urine (25.3%). 10.7% isolates were resistant to Imipenem, followed by Meropenem (12.7%), Piperacillin Tazobactum (14%) and Piperacillin (28.7%). Higher level of resistance was observed with Nitrofurantoin(71.1%), Gentamicin (60.7%), Amikacin (42%), Ciprofloxacin (46%) and Levofloxacin (42%). A total of 43(28.7%) isolates were Multi-Drug resistant. In our hospital, the antibiotic of choice for treatment of infections due to Pseudomonas aeruginosa could be Piperacillin Tazobactum. Emphasis on strict adherence to hospital infection control guidelines and antibiotic policy is also recommended as most of the isolates were recovered from hospitalized patients.


Keywords: Pseudomonas aeruginosa, Antibiotic susceptibility, Treatment
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How to cite this article:

Jayanta Debnath, Anup Saha, Pradip Kumar Das, Niladri Sekhar Das and Soma Saha. 2019. Antibiotic Susceptibility Pattern in Clinical Isolates of Pseudomonas aeruginosa from a Tertiary Care Hospital of TripuraInt.J.Curr.Microbiol.App.Sci. 8(3): 291-298. doi: https://doi.org/10.20546/ijcmas.2019.803.036