National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Candida species are often present as commensal organisms in the healthy individuals, the emergence of Candida species which are resistance to fluconazole has become a great concern globally. Aim of this study was to demonstrate fluconazole resistant pattern of Candida species isolated in various clinical samples. This discriptive Study was carried out in SRM Medical College Hospital & Research centre, Kattankulathur, Kanchipuram, Tamil Nadu, India, between January 2014-2015. Candida species were identified by culture on Sabouraud dextrose agar and confirmed by Gram staining, Germ tube test, Sugar assimilation and fermentation test. Fluconazole resistance was detected by Epsilometric test (E-Test) and the minimum inhibitory concentration (MIC) of the Candida species was measured. Chi square test were used for statistical analysis. A total of 98 Candida species were isolated from 168 clinical specimens, 42.8% of Candida albicans and 57.2% of Candida non albicans were detected, of the 98 isolates 23.4% of Candida species were resistant to fluconazole, highest resistance was seen in Candida krusei (90%). More number of candida non albicans were isolated and showed resistance to fluconazole than candida albicans, hence Candida non albicans should be considered in patient as pathogen and clinically correlate with the infection and presentation of the patient.
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