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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(12): 359-364
DOI: https://doi.org/10.20546/ijcmas.2018.712.044


A Comparative Study to Evaluate Antimicrobial Activity of Hydroalchoholic Extract of Garlic and 2% Chlorhexidine Gluconate Root Canal Irrigant against Enterococcus faecalis (In vitro study)
Manal M. Abdelhafeez1,2 and Nuha Olayan M. Alalweet3
1Department of conservative Dentistry, Collage of Dentistry, Qassim University, Kingdom of Saudi Arabia
2Department of Endodontics, October University for Modern Sciences and Arts, Egypt
3Collage of Dentistry, Qassim University, Kingdom of Saudi Arabia
*Corresponding author
Abstract:

Enterococcus faecalis is the main pathogen detached from failed root canals and insistent peri-apical lesion. It founds in anatomical structures that remain inside inaccessible areas for mechanical instrumentation like lateral canal and isthmus so, the root canal irrigation has an important role in the elimination of microbes in these inaccessible areas for instrumentation. Aim of the study is to compare between the efficiency of a newly introduced product of chlorhexidine gluconate as chemical root canal irrigant and hydroalcoholic extract of garlic herbal product against Enterococcus faecalis. This study was In-vitro used the agar diffusion method. Enterococcus faecalis was cultured on blood agar plate. Thirty three plates were divided into two group Positive and negative control used for verification of the results. Chlorhexidine used as a positive control since it is the commonly used irrigate. The zone of inhibition measured and expressed in millimeters. The results of antibacterial activity were expressed in terms of the diameter of the zone of inhibition. Statistical package for social sciences (SPSS) was used to analyze the data. A descriptive statistics calculated the efficiency of the irrigation solution against Enterococcus faecalis. Student’s T-Test was used. The efficacy of chlorhexidine gluconate was found to be significantly more (18.31±0.946) than Garlic extract (14.71±0.985) against Enterococcus faecalis and the difference was statistically significant p<0.05. 2% chlorhexidine gluconate was shown to inhibit the Enterococcus faecalis effectively. But garlic extract (allicin) as compare to chlorhexidine showed very minimal activity against E. faecalis.


Keywords: Enterococcus faecalis, Chlorhexidine gluconate, Garlic, Mueller Hinton agar, Irrigants
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How to cite this article:

Manal M. Abdelhafeez and Nuha Olayan M. Alalweet. 2018. A Comparative Study to Evaluate Antimicrobial Activity of Hydroalchoholic Extract of Garlic and 2% Chlorhexidine Gluconate Root Canal Irrigant Against Enterococcus faecalis (In vitro study).Int.J.Curr.Microbiol.App.Sci. 7(12): 359-364. doi: https://doi.org/10.20546/ijcmas.2018.712.044