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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(10): 2392-2396
DOI: https://doi.org/10.20546/ijcmas.2018.710.277


Multidrug Resistant Bacteria in Pediatric Patients: A Therapeutic Nightmare
Archana Chintaman Choure1*, Vaishali B. Dohe2, Swati S. Mudshingkar2, Meghana S. Palewar2 and Renu R. Bhardwaj2
1Department of Microbiology, Smt Kashibai Navale Medical College & General Hospital, Pune-411041, India
2Department of Microbiology B. J. Govt. Medical College Pune, India
*Corresponding author
Abstract:

Bacterial infections caused by multidrug resistant bacteria (MDR) are a constant challenge for physicians throughout the world. We processed 451 clinical samples (blood, urine, pus and body fluids) from pediatric patients during the period of July’11 to Oct’11 in Sassoon General Hospital, Pune. Objective is to identify the bacterial isolates from different clinical specimens and study their antibiotics susceptibility pattern. Bacterial infections could be detected in 155 (34.4%) patients. These bacteria were isolated from blood (61%), urine (23%), pus (14%) and body fluid (2%). 64.6% of the infections were from the ward and 35.5% from NICU. 88.4% were gram negative bacilli and 11.7% were gram positive cocci. The most common gram negative bacilli isolated were Pseudomonas aeruginosa (22%) followed by Escherichia coli (15.5%) and Klebsiella pneumoniae (15.5%). 62% of the isolates were MDR, of which 33% were carbapenemase producers. Among the non-fermenters 3.3% organisms were resistant to all drugs including colistin and polymyxin –B. Increasing drug resistant organisms emerging in health care settings is prolonging hospital stay and increasing the cost of health care. So there is an urgent need to formulate guidelines and rationalize the use of antibiotics curtail this pandemic of drug resistance.


Keywords: Multidrug resistant bacteria, Pediatric patients, Antibiotic
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How to cite this article:

Archana Chintaman Choure, Vaishali B. Dohe, Swati S. Mudshingkar, Meghana S. Palewar and Renu R. Bhardwaj. 2018. “Multidrug Resistant Bacteria in Pediatric Patients: A Therapeutic Nightmare”.Int.J.Curr.Microbiol.App.Sci. 7(10): 2392-2396. doi: https://doi.org/10.20546/ijcmas.2018.710.277