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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(10): 1646-1650
DOI: https://doi.org/10.20546/ijcmas.2018.710.187


Comparison of Rapid Immunochromatographic Kits with ELISA for Detection of Dengue in Acute Febrile Cases in a Tertiary Health Care Centre
Ritu Agarwal1*, Gunjan Pandey1 and Niraj Kumar Yadav2
1Department of Microbiology
2Department of Preventive and Social Medicine, G S Medical College & Hospital (Chaudhary Charan Singh University), Pilkhuwa, Uttar Pradesh, India
*Corresponding author
Abstract:

Dengue fever is increasing in incidence each year and with each monsoon season looms a fear of morbidity and mortality by dengue fever Measures by Government to prevent its spread have not been successful to a very large extent and probably require a more intensive approach towards the etiological causes. Until then early diagnosis and treatment remain the key to escape the damage caused by it. To compare Rapid immunochromatography based kits and ELISA which has been the mainstay of diagnosis of dengue. Serum samples from suspected dengue cases were subjected to both RDT and ELISA for detection of N1S antigen, IgG and IgM antibodies. Out of 285 suspected cases, 65 cases were found to be positive for NS1 by both RDT and ELISA whereas IgM and IgG antibody detection was more by ELISA. Diagnosis of dengue by NS1 antigen by RDT is at par with ELISA whereas antibody detection is better by ELISA.


Keywords: Dengue, RDT (Rapid Diagnostic Kit), ELISA
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How to cite this article:

Ritu Agarwal, Gunjan Pandey and Niraj Kumar Yadav. 2018. Comparison of Rapid Immunochromatographic Kits with ELISA for Detection of Dengue in Acute Febrile Cases in a Tertiary Health Care Centre.Int.J.Curr.Microbiol.App.Sci. 7(10): 1646-1650. doi: https://doi.org/10.20546/ijcmas.2018.710.187