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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(10): 819-824
DOI: http://dx.doi.org/10.20546/ijcmas.2016.510.089


Study of Seroprevalence of Dengue Virus Infection in a Tertiary Care Hospital in Patan, Gujarat, India
Ankita Nisarta* and Hitesh Ahir
Department of Microbiology, GMERS Medical College, Dharpur- Patan, Gujarat, India
*Corresponding author
Abstract:

Dengue is a growing public health problem globally including Gujarat. This study is carried out to find out the sero-prevalence of dengue fever in Patan.There are no specific treatment or vaccine against DF or DHF. The outcome of patients with DF or DHF depends significantly on early diagnosis, leading to appropriate clinical management. This study was conducted to report the prevalence of  Dengue virus infection in Patan, Gujarat. Blood samples from clinically suspected dengue cases of GMERS Medical college and hospital, Dharpur-Patan, Gujarat from 2015-2016 were collected. Samples from fever cases <5 days duration were tested for dengue NS1 antigen employing Pan Bio (Australia) NS1 ELISA kit. Serum samples of ≥5 days fever were tested for dengue-specific IgM by MAC ELISA test kit prepared by the National Institute of Virology Pune. Out of  total 90 clinically suspected dengue, 21 were laboratory-confirmed dengue cases. Among the seropositive cases 10(47.61%) were IgM positive, 17(82%) were NS1Ag positive. The majority were males (65%) and in the age group of 16–35 years. Most of the cases were reported in monsoon and post-monsoon periods indicating increased vector transmission .A high percentage of dengue positive cases among suspected patients demands early careful investigation and management.NS1 is useful for early dengue diagnosis, although in terms of cost, ease of performance and rapidity. NS1 in combination with IgM assay offers the most sensitive and cost-effective diagnostic modality for dengue.


Keywords: Dengue diagnosis, NS1 antigen assay,Dengue IgM.
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How to cite this article:

Ankita Nisarta and Hitesh Ahir. 2016. Study of Seroprevalence of Dengue Virus Infection in a Tertiary Care Hospital in Patan, Gujarat, India.Int.J.Curr.Microbiol.App.Sci. 5(10): 819-824. doi: http://dx.doi.org/10.20546/ijcmas.2016.510.089