National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Due to overuse of antibiotics the microbes are becoming resistant to them, so new antimicrobial should be explored which have low MIC and higher efficiency.The present study was conducted to determine the antifungal potential of Streptomyces. Six actinomycetes viz. Streptomyces, Micromonospora, Nocardia sp-1, Nocardia sp-2, Nocardia sp-3 and Streptosporangium were isolated from the soil of KGM Garden and Ganges River Bed, Haridwar. For the evaluation of antimicrobial potential of Streptomyces culture, fermentation of Streptomyces culture was carried out by Shake flask method. Further Streptomyces was taken for antifungal screening against lab fungi Mucor and Aspergillus. Streptomyces was found to inhibit the growth of Mucor 18.3 mm ZOI and Aspergillus 17.6 mm ZOI. After observing the characteristics shown by Streptomyces culture, it can be concluded that the antimicrobial potential in actinomycetes culture may lead to the discovery of new antifungal drugs as it show maximum inhibition against Mucor and Aspergillus comparable to the standard antifungal Nystatin potential.
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