International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:10, October, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(10): 743-748

Antifungal Potential of Actinomycetes isolated from Soil against Pathogenic Fungi
Padma Singh, Rekha Negi*, Alka Rani, Parul and Pallavi
Microbiology Department, Kanya Gurukul Campus, Gurukul Kangri University,Haridwar- 249407, India
*Corresponding author

Due to overuse of antibiotics the microbes are becoming resistant to them, so new antimicrobial should be explored which have low MIC and higher efficiency.The present  study was conducted to determine the antifungal potential of Streptomyces. Six actinomycetes viz. Streptomyces, Micromonospora, Nocardia sp-1, Nocardia sp-2, Nocardia sp-3 and Streptosporangium  were isolated from the soil of KGM Garden and Ganges River Bed, Haridwar. For the evaluation of antimicrobial potential of Streptomyces culture, fermentation of Streptomyces culture was carried out by Shake flask method. Further Streptomyces was taken for antifungal screening against lab fungi Mucor and Aspergillus. Streptomyces was found to inhibit the growth of Mucor 18.3 mm ZOI and Aspergillus 17.6 mm ZOI. After observing the characteristics shown by Streptomyces culture, it can be concluded that the antimicrobial potential in actinomycetes culture may lead to the discovery of new antifungal drugs as it show maximum inhibition against Mucor and Aspergillus comparable to the standard antifungal Nystatin potential.

Keywords: Actinomycetes, Mucor, Aspergillus, Streptomyces, Antifungal.

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How to cite this article:

Padma Singh, Rekha Negi, Alka Rani, Parul and Pallavi. 2016. Antifungal Potential of Actinomycetes isolated from Soil against Pathogenic Fungi.Int.J.Curr.Microbiol.App.Sci. 5(10): 743-748. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.