Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(9): 3464-3470
DOI: https://doi.org/10.20546/ijcmas.2018.709.429


Serum Tumor Necrosis Factor-Alpha (TNF-α) Levels in Children with Nephrotic Syndrome and Its Correlation with Biochemical Parameters
Ammar B. Al-Assadi1, Nidhal A. Mohammed1 and Shatha H. Ali2
1College of Biotechnology, Al-Nahrain University, Iraq
2College of Medicine, Al-Nahrain University, Iraq
*Corresponding author
Abstract:

The aim of this study is to compare the levels of TNF-α in children with nephrotic syndrome and healthy control children and the correlation of TNF-α with clinical feature of NS. Fifty children with NS were divided into four groups: 14 steroid sensitive infrequent relapse (SSIFR), 12 steroid sensitive frequent relapse (SSFR), 9 steroid resistance (SR) and 15 newly diagnosis (ND) compared to twenty-five unrelated healthy children. The serum IL-13 levels for NS patients and healthy control children were measured by R&D quantitative ELISA kit. Serum levels of TNF-α showed highly significant difference between patients with NS (15.68 ± 2.38pg/ml) and healthy control (1.066 ± 0.65pg/ml), and there is no significant different among NS groups. Highly significant correlation between TNF-α mean level and biochemical markers of NS patients also reported in this study.


Keywords: ELISA, SSIFR, SSFR, SR
Download this article as Download

How to cite this article:

Ammar B. Al-Assadi, Nidhal A. Mohammed and Shatha H. Ali. 2018. Serum Tumor Necrosis Factor-Alpha (TNF-α) Levels in Children with Nephrotic Syndrome and Its Correlation with Biochemical Parameters.Int.J.Curr.Microbiol.App.Sci. 7(9): 3464-3470. doi: https://doi.org/10.20546/ijcmas.2018.709.429