Autoimmuno Polyglandular Syndrome type I is a very rare autosomal recessive juvenile disorder characterized by the the triad of mucocutaneous candidiasis, hypoparathyroidism, and adrenal insufficiency requiring at least two of these three components for diagnosis. Here two siblings presented with mucocuteneous Candidiasis and ectodermal dystrophy whereas elder sister developed hypoparathyroidism at this stage, fulfilling the diagnostic criteria of APS I.