International Journal of Current Microbiology and Applied Sciences
ISSN: 2319-7706 Volume 2 Number 9 (2013) pp. 341-346
Anti-proliferative activity of green tea extract in Human Cervical Cancer Cells (HeLa)
B.Geetha and K. S. Santhy*
Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore -641 043, Tamil Nadu, India
In this study antiproliferative effect of Green tea extract was evaluated on HeLa cell line. HeLa cells were cultured in DMEM medium and incubated with different concentrations (18.75, 37.5, 75, 150 and 300 g/ml) of methanol extract of Green tea. Cell viability was assessed by MTT assay. Green tea decreased cell viability in malignant cells in a concentration dependent manner. The IC50 value of green tea extract was found to be 111.9 g/ml. It may be concluded that green tea could cause cell death in HeLa cells and can be considered as a promising antiproliferative agent against cervical carcinogenesis
Anti- proliferative effect; Human cervical Cancer.