International Journal of Current Microbiology and Applied Sciences
ISSN: 2319-7706 Volume 2 Number 8 (2013) pp. 177-186 
Antimicrobial chemotherapy for microorganisms causing male infertility 
S.Sasikumar1 *, E.K.Madhankumar1 , D.Dakshayani1 , A.Franklin2 and Rajkumar Samuel 
1Nova IVI fertility centre, RA.Puram, Chennai, Tamilnadu, India 2Sri Lakshmi Narayana Institute of Medical Sciences, Puducherry, India 3Hubert Enviro Care Systems (P) Ltd, Chennai, Tamil Nadu, India *Corresponding author e-mail: 
Many studies have been performed to examine the effect of semen bacterial infection on the outcome of IVF. The presence of bacteria wanted treatment by antibiotics due to possible adverse effects on semen parameters. Complications arise when determining which bacteria are significant and which merely represent skin contamination. When examining statistics or all patients which positive semen culture. At the time of IVF , it was found no difference in the pregnancy rate when compared with patient with negative culture. It was the notion that bacteria may have an adverse effect on semen parameters and on IVF results. Staphylococcus aureus was the highest prevalent bacteria in the study. Other isolates including Escherichia coli, Klebseilla ozaenae, Proteus vulgaris Pseudomonas aeruginosa also recovered from the semen. These all have been reported to possess invitro spermicidal activity.Antibiotic sensitivity for the isolated organism shows their sensitivity on the antibiotics. The highly sensitive antibiotics were identified Vancomycin, Gatifloxacin, cefoperazone / Sulbactum, Amikacin, Imipenum. Minimum inhibitory concentration of thse antibiotics also determined for the better treatment to the IVF patients. 
IVF; semen parameters; Klebseilla ozaenae; Klebseilla ozaenae; Proteus vulgaris; Pseudomonas aeruginosa; Escherichia coli