International Journal of Current Microbiology and Applied Sciences
ISSN: 2319-7706 Volume 2 Number 8 (2013) pp. 144-147
Better understanding of peritoneal membrane anatomy and physiology - a success behind peritoneal dialysis
S.Lokesh* , and R.ArunKumar 
Department of General Medicine, MGMC&RI, Puducherry, India *Corresponding author e-mail: 
The incidence of non communicable disease is on a rise, more so the Diabetes Mellitus and Hypertension. As a result of increased longevity the end organ dysfunctions are noticed often in Diabetic and hypertensive individuals. In addition there are various primary renal diseases which leads on to End Stage Renal Disease, once ESRD sets in Renal Replacement Therapy (RRT) become mandatory for survival. Peritoneal Dialysis is a form of RRT that has gained enormous popularity due to its simplicity and ease at which it could be performed at home by the patient himself. There has been several changes in the Peritoneal Dialysis technique, catheter insertion, catheter designs, dialysis prescription, management of complications and so on. All these emerged over decades as a result of a better understanding of peritoneal membrane and its functions. Some of the complications which were poorly defined before and were occurring at higher incidence (MIA syndrome, glucotoxicity) now has reduced and are rarely seen in the clinical practice. In this article we describe the anatomical and physiological processes which helped in emergence Peritoneal Dialysis, a novel Renal Replacement Therapy. 
Peritoneal Dialysis; Renal Replacement Therapy; End Stage Renal Disease.