International Journal of Current Microbiology and Applied Sciences

ISSN: 2319-7706 Volume 2 Number 5 (2013) pp. 215-219

Antifungal susceptibility pattern of Candida dublinienses recovered from HIV infected patients

S. R. More, P. C. Sharma*, S. S. Raut and V. S. Rathod

Department of Microbiology, Dr. Shankarrao Chavan Government Medical College, Nanded, Maharashtra, India- 431601 *Corresponding author e-mail: pcsharma.501@gmail.com

A B S T R A C T

Candida dubliniensis is a recently identified yeast, mostly isolated in HIV- positive individuals. it shares diagnostic characteristics with Candida albicans. Oropharyngeal and oesophageal samples from clinically suspected cases of candidiasis were processed in the study. Identification of Candida dublinienses was done by conventional standard techniques using Gram s stain, cultural character on Saboraud dextrose agar, germ tube test, morphology on corn meal agar, colour difference on Hichrome Candida differential agar (CHROM agar) and sugar assimilation test by using HIMEDIA candida identification kit KB006. 25.33% of the Candida isolates were Candida dublinienses. 15.79% were resistant to Fluconazole, 13.16% were resistant to Clotrimazole and 10.53% were resistant to both Ketoconazole and Itraconazole. Emergence of C. dubliniensis infection in HIV seropositive patients is a matter of concern due to the emergence of resistance to commonly used azole antifungals

Keywords

Candida dublinienses; HIV; Fluconazole.