International Journal of Current Microbiology and Applied Sciences

ISSN: 2319-7706 Volume 2 Number 10 (2013) pp. 300-305

Evaluation of antioxidant and antimicrobial potential of cyanobacteria, Chroococcus turgidus (Kützing) Nägeli

M.Bharanidharan* , V.Sivasubramanian and S.Rama Raja Valli Nayagam

Department of Plant Biology and Plant Biotechnology, R.K.M. Vivekananda College, Mylapore, Chennai 600004, India

ABSTRACT

Cyanobacteria are photosynthetic prokaryotes produces a high variety of secondary metabolites that often have potent biological activities. The aim of this study was to assess the effect of crude methanolic and hexane extracts of Chroococcus turgidus against gram positive and gram negative bacterial strains and to assess the antioxidant potential. In the preliminary antimicrobial study, hexane extracts outpaced methanolic extracts against all the seven bacterial strains. The study showed a significant antagonistic activity against all tested bacteria in hexane extracts at different ranges. The largest zone of inhibition (13.3±1.84) was exhibited in V. parahaemolyticus. The lipid peroxidation and iron chelating activity of C. turgidus assessed using TBARs and FRAP assays respectively. The results showed good antioxidant potential with increase of drug dose in both the assays. Gas chromatography-Mass spectroscopy analysis revealed the volatile organic compounds. This investigation revealed that the metabolites produced by C. turgidus can be a potential source of antimicrobial and antioxidant agents.

Keywords

Cyanobacteria; Chroococcus turgidus; antimicrobial study; TBARs and FRAP assays.