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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(9): 1188-1200
DOI: https://doi.org/10.20546/ijcmas.2018.709.141


Sperm Transcriptomics: An Emerging Technique to Assess Male Fertility
Kennady Vijayalakshmy1*, Dharmendra Kumar2, Meenakshi Virmani3, Ninan Jacob1 and Pradeep Kumar2
1Department of Veterinary Physiology, Rajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Puducherry-605 009, India
2Department of Animal Physiology and Reproduction, ICAR-Central Institute for Research on Buffaloes, Hisar-125004, Haryana, India
3Department of Veterinary Physiology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar-125004, Haryana, India
*Corresponding author
Abstract:

Semen sample has to be analyzed to determine the fertilization capacity of sperm. This helps in the efficient use of semen sample for cryopreservation and their further use in artificial insemination. The current methods used to analyze semen just indicate a predictive fertility status, not an actual fertilization capacity. Certain mRNA population / transcripts which are present in spermatozoa are found to have a potential role in fertilization capacity. The analysis of mRNA population in sperm by means of isolation of RNA from sperm and profiling of these mRNA transcripts may give the actual fertilization status of the sperm. This technique is non- invasive in nature and it can be used as promising technique to screen the fertility of male animals at an early stage.


Keywords: Fertility markers, Male infertility, Semen, Sperm mRNA, Transcriptome analysis
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How to cite this article:

Kennady Vijayalakshmy, Dharmendra Kumar, Meenakshi Virmani, Ninan Jacob and Pradeep Kumar. 2018. Sperm Transcriptomics: An Emerging Technique to Assess Male Fertility.Int.J.Curr.Microbiol.App.Sci. 7(9): 1188-1200. doi: https://doi.org/10.20546/ijcmas.2018.709.141