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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(8): 4384-4389
DOI: https://doi.org/10.20546/ijcmas.2018.708.460


Systemic Inflammatory Response Syndrome Associated Alterations in Platelet Indices in Dogs
R. Jasmin1*, M. Balagangatharathilagar1**, S. Vairamuthu2, D. Sumathi1, K. Vijayarani3, M.G. Jayathangaraj1 and G. Ravikumar4
1Department of Veterinary Clinical Medicine
2Centralised Clinical Laboratory
3Department of Animal Biotechnology, Madras Veterinary College, Chennai-600 007, India
4Zoonoses Research Laboratory, Madhavaram Milk Colony, Chennai-600 051, Tamil Nadu Veterinary and Animal Sciences University, India
*Corresponding author
Abstract:

Systemic Inflammatory Syndrome (SIRS) has been recognized as a life threatening condition in both human and small animal patients admitted in critical care units. Septic and non-septic etiologies were documented in the cases with SIRS. Thrombocytopenia and disseminated intravascular coagulopathy (DIC) were consistently observed in many cases with SIRS. Hence, this study was carried out to evaluate the pattern of platelet indices in dogs with Systemic Inflammatory Response Syndrome (SIRS) in comparison with healthy controls. This study evaluated the platelet indices in blood samples obtained from 30 dogs admitted in Critical Care Unit of Madras Veterinary College with SIRS and the results were compared with 10 healthy dogs. Based on physical and hematological examination the dogs with SIRS were classified as SIRS signs with thrombocytopenia (n=15) and SIRS signs without thrombocytopenia (n=15). Blood samples were collected by cephalic venipuncture and analysis was performed using the auto hematology analyzer. The parameters assessed were viz., Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Plateletcrit (PCT). The factorial ANOVA model was used for statistical analysis. The results revealed significant variations in platelet indices viz., MPV, PDW and PCT between the healthy dogs and the dogs with SIRS.


Keywords: Platelet Indices, Thrombocytopenia, SIRS, DIC, Dogs.
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How to cite this article:

Jasmin, R., M. Balagangatharathilagar, S. Vairamuthu, D. Sumathi, K. Vijayarani, M.G. Jayathangaraj and Ravikumar, G. 2018. Systemic Inflammatory Response Syndrome Associated Alterations in Platelet Indices in Dogs.Int.J.Curr.Microbiol.App.Sci. 7(8): 4384-4389. doi: https://doi.org/10.20546/ijcmas.2018.708.460