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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(8): 3956-3964
DOI: https://doi.org/10.20546/ijcmas.2018.708.408


Emergence of Non albicans Candida as a Major Pathogen Isolated from Urine Samples of Patients Attending Tertiary Care Centre, Greater Noida, India
Shaheen Bhat, Tarana Sarwat* and Shalini Bisht
Department of Microbiology, School of Medical Sciences and Research, Sharda University, Greater Noida U.P, India
*Corresponding author
Abstract:

Candida albicans is the most common aetiological agent in candiduria cases commonly observed in hospitalized patients. But a few reports are available from India where non albicans Candida species have accounted for >50 per cent of urinary Candida isolates. We undertook this study to know the Candida species profile amongst candiduria cases. A total of 119 consecutive Candida isolates obtained from clinically suspected cases of urinary tract infection from January 2016 to June 2017 (18 months), were included. Yeast species were identified by standard phenotypic methods. Antifungal susceptibility testing of yeast was performed by disc diffusion method as per Clinical and Laboratory Standards Institute (CLSI) guidelines. The male to female ratio was 0.92. The mean age of patients was 42.7 ± 18.9 yr. C. tropicalis (45.3%) was the most common Candida species followed by C. glabrata (22.6%). All isolates of non-albicans Candida except few C. glabrata, were resistant to fluconazole. None of the isolates showed resistance to Amphotericin B. Non albicans Candida especially C. tropicalis were the predominant fungal pathogens responsible for urinary tract infection. More resistance to fluconazole observed in the study may be due to widespread use of fluconazole in this area.


Keywords: Antifungal susceptibility, Candiduria, C. albicans, non albicans candida
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How to cite this article:

Shaheen Bhat, Tarana Sarwat and Shalini Bisht. 2018. Emergence of Non albicans Candida as a Major Pathogen Isolated from Urine Samples of Patients Attending Tertiary Care Centre, Greater Noida, India.Int.J.Curr.Microbiol.App.Sci. 7(8): 3956-3964. doi: https://doi.org/10.20546/ijcmas.2018.708.408