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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(8): 3849-3854
DOI: https://doi.org/10.20546/ijcmas.2018.708.394


Phenotypic Characterisation of Candida Species from Clinical Isolates in a Tertiary Care Teaching Hospital Hyderabad
S. Swathi1, Taruni2*, Rajkumar Sade3 and Nagababu Pyadala4,5
1Department of Microbiology, MNR Medical College, Hyderabad, Telangana, India
2Department of Microbiology, Government Medical College; Siddipet, Telangana, India
3Department of Surgery, Kamineni Institute of Medical sciences, Narketpally, Telangana State, India
4Department of Clinical Research, Genomix CARL, Pullivendula, A.P., India
5Department of Quality and Control, Genomix Molecular Diagnostics Pvt. Ltd., Hyderabad, Telangana, India
*Corresponding author
Abstract:

Background- Recently fungal infections are increased rapidly due to increase antibiotic use and misuse along with increased use of intravascular devices. Especially colonizing yeast like organisms like Candida species are emerging as important fungal pathogen. Aim- Thus this present study focused on isolation and characterisation of Candida species from various clinical isolates. Materials and methods- the present study was conducted in Department of Microbiology, ESI Medical College and Hospital from April 2017 to May 2018. Various clinical specimens included such as, urine, sputum, high vaginal swab, nail, skin and blood. A total of 1,650 specimens were included in this study. Identification and speciation of Candida isolates were done as per the standard Microbiological procedures. Results- Most of the Candida species was isolated from male patients (62.3%) and 37.73% were female patients. Most common age group affected by candidiasis was 21-40 years (28/52.8%) followed by 41-50 years (14/25.9%). Among all these specimens, urine culture yielded more number of Candida isolates (27/50%) followed by sputum (14/25.9%), high vaginal swab (6/11.1%), nail (3/5.5%), skin (2/3.7%) and blood (2/3.7%). Out of 54 isolates, one was Cryptococcus spp and rest of the isolates were Candida spp. Among 53 Candida species, 32 were isolated as Candida albicans (60.4%), 8 were Candida tropicalis (15.09%), 6 were Candida krusei (11.3%) and 4 were Candida glabrata (7.5%) and 3 were Candida parapsilosis (5.7%). Conclusion- Identification and characterisation has to be done for all Candida isolates along with clinical correlation.


Keywords: Candidiasis, phenotypic characterisation, Candida species
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How to cite this article:

Swathi, S., Taruni, Rajkumar Sade and Nagababu Pyadala. 2018. Phenotypic Characterisation of Candida Species from Clinical Isolates in a Tertiary Care Teaching Hospital Hyderabad.Int.J.Curr.Microbiol.App.Sci. 7(8): 3849-3854. doi: https://doi.org/10.20546/ijcmas.2018.708.394