National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
This study was aimed at investigating the effect of crude oil contaminated feeds on selected serum enzymes and electrolyte levels in Albino wistar rats. Albino wistar rats weighing between 180g to 200g were obtained from Ladoke Akintola University of Technology Ogbomosho, OyoState and used for the study. The animals were grouped into five study groups with six (6) animals in each group. The animals were kept in a well-ventilated room comprising control group, crude oil group, garlic treated group, Vitamin C treated group and Vitamin E treated group. The animals were fed with contaminated feeds 25mg of the antioxidant specified for each group simultaneously for two weeks. However, control group were only fed with the normal while the crude oil group was not treated with the antioxidant. The levels of LDH and GGT concentrations increased significantly (P>0.05) in crude oil only fed group but LDH showed low concentration on treatment with vitamin E(P<0.05).Garlic and vitamin C therefore do not have ameliorative effect on increased LDH and GGT levels of crude oil contamination. Vitamin E therefore reduced the toxic effect of the crude oil contamination on LDH significantly after 28 days. There was a significant increased (P>0.05) in the activities of AST, ALT, ALP in groups fed with crude oil contaminated diet when compared to the control and these sharp changes were ameliorated after 28 days of antioxidant treated groups.
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