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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(9): 549-554
DOI: http://dx.doi.org/10.20546/ijcmas.2016.509.061


Change in Antibiotic Sensitivity Pattern of Klebsiella pneumoniae: A Two and Half Year Study
Krunal Shah*, S. Suguna Hemachander, S.J. Lakhani and Radhika Khara
Department of Microbiology, SBKS Mi & RC, Sumandeep Vidyapeeth, Waghodia,Vadodara, Gujarat, India  
*Corresponding author
Abstract:

In the era of drug resistant microorganisms, we are left with very few choices of antibiotics. Klebsiella pneumoniae is among the most common gram negative bacteria encountered by physicians worldwide which were often resistant to many antibiotics. This study was aimed to evaluate change in Antibiotic Susceptibility pattern of Klebsiella pneumoniae isolated from various clinical samples over a period of Two and a Half year which can guide future treatment option for this organism. Total of 416 Klebsiella pneumonia isolated from various clinical samples and their antibiotic sensitivity were studied. Antibiotic Susceptibility pattern showed change in sensitivity pattern for most of the antibiotics over a period of time. Imipenem showed much reduction in sensitivity 94.25% in February 2014 – January 2015, 70.76 % in February 2015 – January 2016 and 36.17 % in February 2016 – July 2016. Increase in susceptibility towards Gentamicin (from 16.66 % to 29.78 %) and Amikacin (29.31 % to 40.42 %) was observed.


Keywords: Klebsiella pneumoniae, Antibiotic Susceptibility pattern,Imipenem.
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How to cite this article:

Krunal Shah, S. Suguna Hemachander, S.J. Lakhani and Radhika Khara. 2016. Change in Antibiotic Sensitivity Pattern of Klebsiella pneumoniae: A Two and Half Year Study.Int.J.Curr.Microbiol.App.Sci. 5(9): 549-554. doi: http://dx.doi.org/10.20546/ijcmas.2016.509.061