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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(5): 3363-3369
DOI: https://doi.org/10.20546/ijcmas.2018.705.393


Antibiotic Resistance Pattern of the Blood Culture Isolates of Adult Sepsis Patients from a Rural Based Tertiary Care and Teaching Hospital, Piparia, Vadodara
Radhika Khara and Sucheta J. Lakhani
Department of Microbiology, SBKS MI & RC, Piparia, Waghodia, Gujarat, India
*Corresponding author
Abstract:

The rapid emergence of resistance against the antibiotics by bacteria poses a threat to the health and health benefits that can be obtained by the use of antibiotics. This problem is worldwide and it reflects on the overuse of these drugs and lack of development of new drugs for combating this situation. Moreover infections due to such resistant bacteria add to the cost of healthcare in any nation. Thus performing antibiotic susceptibility and accordingly choosing the right antibiotic in each case to be treated invasive infections or non-invasive infections will prevent unjustified use of antibiotics as well as helps generate data regarding resistant bacteria and development of policies to prevent antibiotic resistance. A total of 673 blood cultures were performed from 743 clinically diagnosed sepsis patients. A total of 339 isolates were obtained from 330 (49.18%) blood culture positive samples. Of the 339 isolates, 51.32% (174/339) were Gram negative bacilli, 38.64% (131/339) were Gram positive bacteria and 10.02% (34/339) Candida species. All the bacterial isolates, gram positive as well as gram negative were subjected to antibiotic susceptibility testing by Kirby-Bauer disc diffusion method. Least resistance was observed against cabapenems i.e. 21.8% with 10.26% against Imipenem and 11.54% against Ertapenem and Meropenem with Acinetobacter spp. showing the highest resistance i.e. 29.63% whereas the most was seen against Cefuroxime, Cefotaxime and Ceftazidime.


Keywords: Sepsis, Blood culture, Antibiotics, Resistance
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How to cite this article:

Radhika Khara and Sucheta J. Lakhani. 2018. Antibiotic Resistance Pattern of the Blood Culture Isolates of Adult Sepsis Patients from a Rural Based Tertiary Care and Teaching Hospital, Piparia, Vadodara.Int.J.Curr.Microbiol.App.Sci. 7(5): 3363-3369. doi: https://doi.org/10.20546/ijcmas.2018.705.393