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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(5): 1554-1560
DOI: https://doi.org/10.20546/ijcmas.2018.705.184


Morphology, Distribution and Functional Significance of Dendritic Cells (DCs) in the Skin of Domestic Animals
R. Gnanadevi1, T.A. Kannan2*, S. Ushakumary1 and Geetha Ramesh1
1Department of Veterinary Anatomy, Madras Veterinary College, Chennai-600 007, India
2Centre for Stem Cell Research and Regenerative Medicine, Madras Veterinary College, Chennai-600 007, India
*Corresponding author
Abstract:

In mammals, skin is the largest of the body's organs which provides an immediate and excellent barrier between the internal tissues and external environment. Dendritic cells are antigen presenting cells which regulate the immune responses. The present study, aimed to describe the morphology and distribution of dendritic cells present among the skin of cattle, buffalo, sheep and goat. Dendritic cells were stained using Osmium tetroxide solution. The dendritic cells were mostly located in the basal layer at epidermis except small ruminats wherein the cells were mostly in the dermis. Morphology of the DCs also exhibited variations between these domestic animal species. Two types of DCs namely typical dendritic cells and atypical dendritic cells were observed in this study. Both the cell types showed the presence of intra cytoplasmic birbek granules. Typical dendritic cell morphology were found to be more in buffalo skin. The number of DCs from most numerous to least in number in the present study as follows: buffalo, cattle, sheep and goat. The number of dendritic cell in the present study indicated the incidence or prevalence of skin diseases was least in buffalo followed by cattle and more incidence of skin diseases in sheep and goat.


Keywords: Skin, Dendritic cells, Morphology, Distribution, Domestic animal species
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How to cite this article:

Gnanadevi, R., T.A. Kannan, S. Ushakumary and Geetha Ramesh. 2018. Morphology, Distribution and Functional Significance of Dendritic Cells (DCs) in the Skin of Domestic Animals.Int.J.Curr.Microbiol.App.Sci. 7(5): 1554-1560. doi: https://doi.org/10.20546/ijcmas.2018.705.184