Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(5): 1133-1142
DOI: https://doi.org/10.20546/ijcmas.2018.705.138


Asymptomatic Bacteriuria in Pregnant Women - Study at a Tertiary Maternity care Hospital in Hyderabad
V. Mallikarjun Rao1, B.M. Shanker Venkatesh2* and S. Rajeshwer Rao3
1Department of Microbiology Shadan Medical College, Hyderabad, Telangana, India
2Department of Microbiology Osmania Medical College Hyderabad, Telangana, India
3Department of Microbiology Gandhi Medical College, Hyderabad, Telangana, India
*Corresponding author
Abstract:

Urinary Tract Infections (UTIs) commonly occurs in pregnancy, due to the morphological and physiological changes that take place in the genitourinary tract.Asymptomatic bacteriuria refers to the presence of bacteria in urine, and is a condition in which urine culture reveals a significant growth of pathogens that is greater than 105 bacteria/ml, but without the patient showing symptoms (Gilbert et al., 2005). The apparent reduction in immunity of pregnant women appears to encourage the growth of both commensal and non-commensal microorganisms (Scott et al., 1990). The most untoward consequence of Asymptomatic bacteriuria in pregnancy is severe renal damage. Asymptomatic bacteriuria in some woman may lead to pyelonephritis or cystitis during pregnancy, while in others there may be no symptoms of urinary tract infection through-out gestation, but may develop urinary tract infection during puerperium. Pregnancy enhances the progression from asymptomatic to symptomatic bacteriuria which could lead to pyelonephritis and adverse obstetric outcomes such as prematurity, low birth weight (Connolly and Thorp, 1999) and higher fetal mortality rates (Nicolle, 1994; Delzell and Leferre, 2000). This study therefore was carried out to determine the prevalence of Asymptomatic bacteriuria (ASB) in pregnant women and to isolate, identify the causative organisms; and to test the antimicrobial susceptibility of isolated pathogens. A total of 200 pregnant women who came for ante-natal checkup in outpatient department at Govt. Maternity Hospital, Nayapool. Hyderabad were studied over a period of one year. Clean catch midstream urine sample was collected into a sterile container and then subjected to culture method. Out of 200 patients studied, significant bacteriuria was noted in 36 (18%) cases and 8(4%) patients had insignificant bacteriuria. Highest incidence of 22 cases (61.11%) were reported in the age group of 26-35 years. It was found that Asymptomatic bacteriuria showed significant increase with respect to parity, higher incidence was seen in multi gravidae 58.9% (3 and 4th parity). Incidence of Asymptomatic bacteriuria was found to decrease with the increase in gestation time, maximum number were noted in first trimester 19 (52.78%) followed next by second trimester 13 (36.11%) and in third trimester 4 (11.11%). E. coli 20 (55.56%),was the most common etiological agent followed by Klebsiella spp in 9 cases (25%) Coagulase negative Staphylococcus in 2 cases (5.56%) and Pseudomonas spp in 2 cases (5.56%), Proteus mirabilis and Enterobacter, Staphylococcus aureus each in one case (2.78%) all the strains were sensitive to imipenem and meropenem. As asymptomatic bacteriuria is associated with complications in pregnancy, it is therefore imperative that pregnant women be screened for bacteriuria, periodically in every trimester of the gestational period. Routine urine culture tests should be carried out for all antenatal women to detect asymptomatic bacteriuria, and every positive case should be treated with appropriate antibiotic therapy, to prevent any obstetric complication which is associated with pregnancy. In view of changing patterns of bacterial resistance to common drugs, the importance of educating physicians on use of antibiotics accordingly to provide empirical therapy is important.


Keywords: UTI, Asymptomatic bacteruria, E. coli
Download this article as Download

How to cite this article:

Mallikarjun Rao, V., B.M. Shanker Venkatesh and Rajeshwer Rao, S. 2018. Asymptomatic Bacteriuria in Pregnant Women - Study at a Tertiary Maternity care Hospital in HyderabadInt.J.Curr.Microbiol.App.Sci. 7(5): 1133-1142. doi: https://doi.org/10.20546/ijcmas.2018.705.138