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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(5): 697-707
DOI: https://doi.org/10.20546/ijcmas.2018.705.084


Study of Central-Line Associated Blood Stream Infections (CLABSIs) and Central-Line Related Blood Stream Infections (CRBSIs) in a Tertiary Hospital, Bangalore, India
C. Bhavana*, T. Nagarathnamma and R. Ambica
Department of Microbiology, Bangalore Medical College and Research Institute, Karnataka, India
*Corresponding author
Abstract:

Bloodstream infections caused by central venous catheter remains a serious and the most common cause of Hospital acquired infections (HAIs) worldwide. Central line-associated bloodstream infections remain a leading cause of serious healthcare-associated infections in ICUs in India, the rate being 7.9 per 1000 central line-days. Accurate measurement of the rates of BSIs arising from catheters is important because ICUs with high rates will need to institute further performance improvement initiatives in CVC insertion and management. The main aims of this study were to identify the various factors influencing the infections associated with CVC, the rate of infections associated with CVC, to identify the organisms involved in the causation of Central-line associated blood stream infections (CLABSIs) and Central-line related blood stream infections (CRBSIs) and to study the antibiotic susceptibility patterns of the isolated organisms. The present study revealed that rate of CLABSI was 8.26/1000 central-line days and CRBSI was 0.26/1000 central-line days mostly affecting the age group 51-60 years and males were more commonly than females. Staphylococci were the most common organism isolated. The study showed high incidence of resistance against conventional antibiotics such as Ampicillin, Amoxycillin-clavulanate, Gentamicin, Amikacin, Erythromycin and Azithromycin among the pathogens causing CLABSI/CRBSI. Since CVCs are increasingly being used in the critical care, regular surveillance for infections associated with them is essential. There is a change in the pattern on pathogens causing the bloodstream infections and their susceptibility pattern as compared to other studies. Hence, it is very important for strengthening of the infection control, instituting surveillance systems, and implementing evidence-based preventive strategies in order to prevent bloodstream infections caused by CVCs.


Keywords: Central line-associated bloodstream infections, Central line-related bloodstream infections, Surveillance
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How to cite this article:

Bhavana, C., T. Nagarathnamma and Ambica, R. 2018. Study of Central-Line Associated Blood Stream Infections (CLABSIs) and Central-Line Related Blood Stream Infections (CRBSIs) in a Tertiary Hospital, Bangalore, India.Int.J.Curr.Microbiol.App.Sci. 7(5): 697-707. doi: https://doi.org/10.20546/ijcmas.2018.705.084