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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(5): 288-297
DOI: https://doi.org/10.20546/ijcmas.2018.705.037


Microbial Profile and their Susceptibility Pattern in Ventilator Associated Pneumonia in a Tertiary Care Hospital
B. Shanthi, R. Selvi*, V. Sheeba and P. Ponnammal
Stanley Medical College, Chennai – 600001, Tamil Nadu, India
*Corresponding author
Abstract:

Ventilator Associated Pneumonia (VAP) is the most common intensive care unit (ICU) acquired nosocomial infection and it is considered as the second most common hospital acquired infection associated with higher mortality and morbidity. The aim of this study was to determine the microbial profile of pathogens causing VAP and their antibiotic susceptibility patterns over a period of five years in the intensive care unit (ICU) of a tertiary care hospital. Cross-sectional, descriptive study was done on patients who were on mechanical ventilation for more than 48 hours and clinically suspected of having pneumonia for the five consecutive years 2012 to 2016. During the study period significant growth of pathogens were found in 216 / 581patients. 90.27% were monomicrobial 9.72% were polymicrobial. Pseudomonas aeruginosa was the most commonly isolated gram-negative bacteria 69 /206 (33.49 %) followed by Klebsiella species 59 (28.64%). An increase in resistance was shown by Pseudomonas aeruginosa and Acinetobacter spp. 58.49 % of Klebsiella spp and 52.00 % of Escherichia coli were ESBL producers. Staphylococcus aureus was the most commonly isolated gram positive bacteria (24), 18 (75%) were Methicillin resistant (MRSA). Good management strategies for VAP like adequate infection control practices include hand washing by hospital personel, basic cleaning of all surface levels, increased barrier precautions, early accurate diagnosis and more specific antimicrobial use may significantly improve patients’ outcome.


Keywords: Ventilator Associated Pneumonia (VAP), Intensive care unit, Antibiotic resistance
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How to cite this article:

Shanthi, B., R. Selvi, V. Sheeba and Ponnammal, P. 2018. Microbial Profile and their Susceptibility Pattern in Ventilator Associated Pneumonia in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 7(5): 288-297. doi: https://doi.org/10.20546/ijcmas.2018.705.037