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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(4): 2897-2902
DOI: https://doi.org/10.20546/ijcmas.2018.704.330


A Comparative Study of Rapid Salmonella-IgM Test (Typhi-dot M) and Widal Test in the Diagnosis of Enteric Fever in a Tertiary Hospital
V. Mallikarjun Rao
Department of Microbiology, Shadan Institute of Medical Sciences and Research Centre, Hyderabad, Telangana, India
*Corresponding author
Abstract:

Typhoid fever is a noted cause of morbidity worldwide and a major public health problem in India and other developing countries. An early and accurate diagnosis is essential for a prompt and effective treatment. The present study was conducted with the aim of comparing the efficacy of rapid Salmonella‑IgM test (Typhi-dot M) and Widal test in both blood culture positive and negative patients in the diagnosis of enteric fever in a tertiary hospital. A total 794 patients serum samples were tested by rapid Salmonella‑IgM test (Typhi-dot M), Widal test and blood culture. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of Typhidot‑IgM test, considering blood culture positive for S. typhi as gold standard, were 93.04%, 80.08 %, 74.14% and 94.93 % respectively and 36.09%, 58.53%, 34.82% and 59.87% respectively for Widal test. Rapid Salmonella‑IgM test (Typhi-dot M) is significantly more sensitive and specific as compared to Widal test in the diagnosis of enteric fever. It can be utilized in conjunction with blood culture for diagnosis of enteric fever.


Keywords: Enteric fever, Blood culture, Rapid salmonella-IgM test, Typhidot-IgM, Widal test
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How to cite this article:

Mallikarjun Rao, V. 2018. A Comparative Study of Rapid Salmonella-IgM Test (Typhi-dot M) and Widal Test in the Diagnosis of Enteric Fever in a Tertiary Hospital.Int.J.Curr.Microbiol.App.Sci. 7(4): 2897-2902. doi: https://doi.org/10.20546/ijcmas.2018.704.330