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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(4): 2656-2663
DOI: https://doi.org/10.20546/ijcmas.2018.704.303


Comparative Efficacy of Melia azedarach Extracts with Amprolium against Experimentally Induced Coccidiosis in Broilers
S. Shekhar1*, S.K. Shukla2, Prakash Bhatt3, Mahesh Kumar2 and D.S. Bisth4
1Krishi Vigyan Kendra (ICAR-NRRI), Jainagar, Koderma, Jharkhand- 825324, India
2Department of Veterinary Medicine, 3Department of Veterinary Clinics, 4Department of Veterinary Surgery, C.V.A.Sc., Pantnagar, G.B.P.U.A.T,
Pantnagar-264145, Uttarakhand, India
*Corresponding author
Abstract:

The present study was planned to investigate the alternative and economical way for treating caecal coccidiosis in Broilers. An experiment was conducted to evaluate the anticoccidial efficacy of aqueous and methanolic extract of Melia azedarach (Bakain) leaves in experimentally induced Eimeria tenella infection in Broilers. Acute toxicity test of herbal extract was conducted in 21 days old broiler. The birds were observed 24 hours for sign of toxicity. At three weeks of age the chicks were randomly divided in to eight groups each group having 15 birds. Group I were healthy control, Group II, III and V were uninfected medicated control group received Amprolium @ 250 mg/l, water, aqueous extract of Melia azedarach leaves @1000mg/kg body weight, methanolic extract of Melia azedarach leaves @ 1000mg/kg body weight, on day 21 to 28 day of age, once daily respectively, Group IV, Group VI, VII and VIII were infected with 40,000 infected oocysts of Eimeria tenella at 21 days of age. Birds of group IV, VI and VII were treated with Amprolium @ 250 mg/l water, aqueous extract of Melia azedarach leaves @1000mg/kg body weight, and methanolic extract of Melia azedarach leaves @1000mg/kg body on day 0 to7 day of post infection respectively. Group VIII kept as infected control and not receive any medicine. No sign of toxicity seen during the acute toxicity test even at highest dose. The birds treated with methanolic extract of Melia azedarach leaves resulted in progressively decrease in severity of clinical sign, faecal score, percent survival, percent weight gain, performance index, average oocyst production, per cent reduction in oocyst production, average oocyst index, average lesion score and percent protection against lesion and restorations of haematological and bio chemicals parameters. The result of this study indicated that methanolic extract of Melia azedarach leaves @1000mg/kg body weight for 7 day having has better anticoccidial activity without affecting the growth of broiler.


Keywords: Melia azedarach, Amprolium, Coccidiosis
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How to cite this article:

Shekhar, S., S.K. Shukla, Prakash Bhatt, Mahesh Kumar and Bisth, D.S. 2018. Comparative Efficacy of Melia azedarach Extracts with Amprolium against Experimentally Induced Coccidiosis in Broilers.Int.J.Curr.Microbiol.App.Sci. 7(4): 2656-2663. doi: https://doi.org/10.20546/ijcmas.2018.704.303