National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was planned to investigate the alternative and economical way for treating caecal coccidiosis in Broilers. An experiment was conducted to evaluate the anticoccidial efficacy of aqueous and methanolic extract of Melia azedarach (Bakain) leaves in experimentally induced Eimeria tenella infection in Broilers. Acute toxicity test of herbal extract was conducted in 21 days old broiler. The birds were observed 24 hours for sign of toxicity. At three weeks of age the chicks were randomly divided in to eight groups each group having 15 birds. Group I were healthy control, Group II, III and V were uninfected medicated control group received Amprolium @ 250 mg/l, water, aqueous extract of Melia azedarach leaves @1000mg/kg body weight, methanolic extract of Melia azedarach leaves @ 1000mg/kg body weight, on day 21 to 28 day of age, once daily respectively, Group IV, Group VI, VII and VIII were infected with 40,000 infected oocysts of Eimeria tenella at 21 days of age. Birds of group IV, VI and VII were treated with Amprolium @ 250 mg/l water, aqueous extract of Melia azedarach leaves @1000mg/kg body weight, and methanolic extract of Melia azedarach leaves @1000mg/kg body on day 0 to7 day of post infection respectively. Group VIII kept as infected control and not receive any medicine. No sign of toxicity seen during the acute toxicity test even at highest dose. The birds treated with methanolic extract of Melia azedarach leaves resulted in progressively decrease in severity of clinical sign, faecal score, percent survival, percent weight gain, performance index, average oocyst production, per cent reduction in oocyst production, average oocyst index, average lesion score and percent protection against lesion and restorations of haematological and bio chemicals parameters. The result of this study indicated that methanolic extract of Melia azedarach leaves @1000mg/kg body weight for 7 day having has better anticoccidial activity without affecting the growth of broiler.
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