National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary tract infection (UTI) is an important cause of morbidity in infants. The incidence of UTI is more common among boys. Inappropriately treated cases of UTI can further lead to major acute complications such as cystitis, pyelonephritis, bacteremia. Timely diagnosis and treatment is of paramount importance to prevent rare but serious complications. The objective of this study is to isolate and identify the organisms causing UTI in infants and to study antibiotic susceptibility pattern of the isolated organisms. In this cross-sectional prospective study, 480 infants with suspected of urinary tract infection, were evaluated at Smth Kashibai Navale medical college and general hospital between October 2016 to September 2017. Urine was collected by clean catch mid-stream technique or suprapubic aspiration and sent for culture sensitivity. After identifying bacteria, antimicrobial susceptibility testing was performed by the Kirby-Bauer disc diffusion method. The results were interpreted according to the Clinical and Laboratory Standards Institute (CLSI) guidelines 2013. Most common symptom was fever with suspected UTI. Of 480 UTI suspected cases 192(40%) was culture positive. In present study there was male preponderance. Majority of the isolates were gram negative bacilli followed by gram positive cocci. The most common organism was E. coli, Enterococcus Klebsiella species. Majority of gram negative organisms were sensitive to amikacin, nitrofurantoin, gentamicin and imipenem while gram positive cocci were sensitive to nitrofurantoin, vancomycin, and teicoplanin. Overall susceptibility test showed the highest resistance to ampicillin and cotrimaxazole (TMP-SMX). Urinary tract infection is common in infants and it varies with age and gender. Appropriate evaluation of infants with history, physical examination, urine analysis and microbiological testing of urine should be mandatory. This study highlights the better efficacy of nitrofurantoin and aminoglycosides, imipenam and can be included as empirical therapy.
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