National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary tract infections are the commonest infectious disease, seeking medical consultation and antibiotic therapy worldwide. Klebsiella pneumonia is among the most common uropathogen responsible for recurrent infections and it antimicrobial susceptibility to commonly prescribed drugs vary significantly in different regions. Hence, the objective was to analyze the local etiology and antimicrobial susceptibility pattern of urinary K. pneumonia, to optimize the rational empirical therapy. The current study was carried out for a period of one year from March 2016 to February 2017 in a tertiary care centre. Klebsiella pneumonia isolated in this study were 13.8% (217) of the total isolates and ESBL producing strains were 17.5% (38), out of which 31 (81.5%) were isolated from hospitalized inpatients. Antibiotic susceptibility pattern revealed that the most effective antimicrobials were Imipenem (91.2%), Nitrofurantoin (81.6%) and Amikacin (79.7%) and followed by Ceftazidime (70%) and Ceftriaxone (63%). The isolates showed least susceptibility to Ampicillin (19%), Trimethoprim-Sulphamethoxazole (28.6%) and Ciprofloxacin (42%). This study emphasizes the importance of current knowledge of the uropathogens and their susceptibility pattern for the initiation of appropriate empirical therapy and to minimize the evolving resistant strains.
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