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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(4): 969-973
DOI: https://doi.org/10.20546/ijcmas.2018.704.103


A Study on Prevalence and Antimicrobial Resistance Pattern of Urinary Klebsiella pneumoniae in a Tertiary Care Centre in South India
V. Dillirani1 and R. Suresh2*
1Department of Microbiology, Stanley Medical College, Chennai 600001, India
2Department of Microbiology, Chengalpattu Medical College, Chengalpattu 603001, India
*Corresponding author
Abstract:

Urinary tract infections are the commonest infectious disease, seeking medical consultation and antibiotic therapy worldwide. Klebsiella pneumonia is among the most common uropathogen responsible for recurrent infections and it antimicrobial susceptibility to commonly prescribed drugs vary significantly in different regions. Hence, the objective was to analyze the local etiology and antimicrobial susceptibility pattern of urinary K. pneumonia, to optimize the rational empirical therapy. The current study was carried out for a period of one year from March 2016 to February 2017 in a tertiary care centre. Klebsiella pneumonia isolated in this study were 13.8% (217) of the total isolates and ESBL producing strains were 17.5% (38), out of which 31 (81.5%) were isolated from hospitalized inpatients. Antibiotic susceptibility pattern revealed that the most effective antimicrobials were Imipenem (91.2%), Nitrofurantoin (81.6%) and Amikacin (79.7%) and followed by Ceftazidime (70%) and Ceftriaxone (63%). The isolates showed least susceptibility to Ampicillin (19%), Trimethoprim-Sulphamethoxazole (28.6%) and Ciprofloxacin (42%). This study emphasizes the importance of current knowledge of the uropathogens and their susceptibility pattern for the initiation of appropriate empirical therapy and to minimize the evolving resistant strains.


Keywords: Urinary tract infections, Klebsiella pneumonia, Antimicrobial resistance, Extended spectrum beta lactamases
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How to cite this article:

Dillirani, V. and Suresh, R. 2018. A Study on Prevalence and Antimicrobial Resistance Pattern of Urinary Klebsiella pneumoniae in a Tertiary Care Centre in South India.Int.J.Curr.Microbiol.App.Sci. 7(4): 969-973. doi: https://doi.org/10.20546/ijcmas.2018.704.103