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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(3): 3402-3409
DOI: https://doi.org/10.20546/ijcmas.2018.703.392


Prevalence of Extended Spectrum Β-Lactamase (ESBL) Producing Bacteria among the Clinical Samples in and around a Tertiary Care Centre in Nerul, Navi Mumbai, India
Betsy Andrews, Shrikrishna Joshi*, Rita Swaminathan, Jyoti Sonawane and Keertana Shetty
D Y Patil Medical College and Hospital, Nerul, India
*Corresponding author
Abstract:

To study the prevalence of extended spectrum β-lactamase (ESBL) producing bacteria and its sensitivity pattern to commonly used antibiotics in a tertiary care centre in Navi Mumbai. The study was conducted from June 2016 to July 2017 in Microbiology Department of our tertiary health care centre. A total of 2850 sample was studied, out of which 812 (54.79%) ESBL producing bacteria was detected by using Clinical Laboratory Standard Institute (CLSI) guidelines that described the phenotypic confirmatory test along with routine antibiotic susceptibility testing. ESBL production was confirmed in 812 (54.79%) isolates. The isolates of E. coli (45.50%) were the most common ESBL producers. Maximum ESBL isolates were obtained from urine samples (44.3%) and male patients (56.4%). Surgical ward showed highest prevalence (21.1%) and age group between 51 and 60 were mostly affected (19.9%). This study conducted in D Y Patil Hospital, Nerul, Navi Mumbai shows high prevalence of ESBL production among Gram negative bacteria. E.coli showed highest prevalence i.e. 45.5%. Colistin showed 100% sensitivity followed by Imipenem which showed 98.2%. Prevalence of ESBL producers was more prevalent in urine sample among males than females. Timely administration of sensitive antibiotic and avoiding antibiotic abuse will help to lessen the burden of ESBL producers.


Keywords: Antibiotic abuse, Extended spectrum β-lactamase
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How to cite this article:

Betsy Andrews, Shrikrishna Joshi, Rita Swaminathan, Jyoti Sonawane and Keertana Shetty. 2018. Prevalence of Extended Spectrum Β-Lactamase (ESBL) Producing Bacteria among the Clinical Samples in and around a Tertiary Care Centre in Nerul, Navi Mumbai, India.Int.J.Curr.Microbiol.App.Sci. 7(3): 3402-3409. doi: https://doi.org/10.20546/ijcmas.2018.703.392