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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 7, Issue:3, March, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(3): 2475-2501
DOI: https://doi.org/10.20546/ijcmas.2018.703.288


Gastritis and Peptic Ulcer Diseases in Dogs: A Review
Pankaj Kumar Patel1, Sawita Kumari Patel2, S.K. Dixit1* and R.S. Rathore2
1Division of Medicine
2Division of Veterinary Public Health, ICAR-Indian Veterinary Research Institute, Izatnagar, UP-243122, India
*Corresponding author
Abstract:

The most common clinical condition reported in dogs is acid related diseases in the stomach like gastric disorders due to a structural and functional defect in gastric mucosa. The most important factor for the development of gastritis, peptic ulcer disease and gastric cancer in human is Helicobacter pylori. In the cases of gastric disorder lesions in canine gastric mucosa is closely similar to their human counterparts. Many etiological factors are responsible for oxidative stress due to excessive generation of reactive oxygen species as a cause of gastric mucosal damage. The bacteria exist lifelong in the stomach of the untreated patient. This article reviews the classification, some possible etiopathogenesis, diagnosis and possible differential diagnosis and major strategies of therapy against acid disorders (Fluid therapy, proton pump inhibitors, H-2 blocker, cytoprotective) with an update on the management of oxidative stress with antioxidant therapy (Ascorbic acid, N-acetyl cysteine, Vitamin E) and “Triple therapy” for management of Helicobacter pylori induced gastric disorders.


Keywords: Antioxidant therapy, Gastric mucosa, Helicobacter pylori, Oxidative stress, Triple therapy

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How to cite this article:

Pankaj Kumar Patel, Sawita Kumari Patel S.K. Dixit and Rathore, R.S. 2018. Gastritis and Peptic Ulcer Diseases in Dogs: A Review.Int.J.Curr.Microbiol.App.Sci. 7(3): 2475-2501. doi: https://doi.org/10.20546/ijcmas.2018.703.288
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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