National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Staphylococcus aureus (S. aureus) is a major pathogen associated with serious community and hospital-acquired infections. Methicillin resistant S. aureus (MRSA) is now endemic in India. Methicillin-resistant Staphylococcus aureus (MRSA) has recently emerged as a major nosocomial pathogen worldwide with a significant morbidity and mortality. Early detection of emerging trends in antimicrobial resistance may facilitate implementation of effective control measures. The present study thus attempts to characterize the MRSA isolates and explore the antibiotic susceptibility pattern of MRSA isolated from wound samples at a tertiary care hospital, Central India. The present study was conducted to characterize 120 MRSA isolates, isolated from wound samples and their antibiotic susceptibility patterns. MRSA was identified by oxacillin disc diffusion test, cefoxitin disc diffusion test and resistance to oxacillin by the Minimum inhibitory concentration (MIC) method. Study also detected inducible clindamycin resistance in Staphylococcus aureus. About 120 MRSA isolates from various clinical samples such as such as pus swabs and aspirates, blood, urine, sputum and endotracheal tube aspirates were collected and processed in the laboratory for various tests. All the 120 MRSA strains were 59.17% resistant to mupirocin, 55.83% resistant to ciprofloxacin, 46.67% resistant to Erythromycin, 48.33% to co-trimoxazole, 30% to tetracycline, 21.67% to gentamycin. However, all (100%) MRSA strains were sensitive to vancomycin and linezolid. MRSA showed highest distribution in medical ward as it is a nosocomial pathogen and patients usually acquire it during hospital stay. The treatment of MRSA can become a challenge in the near future. Overuse and misuse of antibiotics along with self-medication should be avoided.
Citations |
 |
 |
 |
 |
