National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The occurrence, severity and mortality rates in human sepsis are increasing worldwide despite an increasing numerous clinical and experimental studies investigating sepsis. Sepsis is a severe clinical syndrome associated to the host response to infection. An auto-amplifying cytokine production: the cytokine storm is the main reason leading to the severity of infections. Cytokines are a large group of protein molecules that control the immune response during the inflammation in the body. Although, advancing in our knowledge about the processes that activate release great amount of cytokines, these understandings could not translate yet into effective treatments and diagnosis. This review aims to summarize our knowledge about most important inflammatory mediators in sepsis pathophysiology.
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