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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(7): 542-549
DOI: http://dx.doi.org/10.20546/ijcmas.2016.507.059


Screening of Antimicrobial Potential of Barleria prionitis Linn Aerial Parts against Common Respiratory Tract Pathogens
Ajeet Singh*, Vinay Mohan Pathak and Navneet
Department of Botany and Microbiology Gurukul Kangri University,Haridwar, Uttrakhand India  
*Corresponding author
Abstract:

The antimicrobial potential of Barleria prionitis Linn. (Aerial parts) were evaluated against common respiratory tract infections causing bacterial and fungal pathogens. The pathogens used in this study were Streptococcus pneumoniae (MTCC 655), Staphylococcus aureus (MTCC 1144), Pseudomonas aeruginosa (MTCC 2474), Streptococcus pyogens (MTCC 442), Haemophillus influenzae (MTCC 3826) and two fungal strains Candida albicans (MTCC 227), Aspergillus niger (MTCC 921). Antibacterial and antifungal activities were determined by Agar well diffusion method, poison food technique, respectively. Erythromycin and fuconazole were used as positive control to establish the sensitivity of bacterial and fungal strains respectively. Methanol (MeOH) extract was found most active followed by ACE, H2O and PET respectively. The maximum inhibition zone was found against S. pneumoniae (19.40±0.64 mm) followed by S. aureus (18.73±0.80 mm), P. aeruginosa (14.98±0.28 mm), S. pyogens (14.2±0.47 mm), H. influenzae (10.11±0.21 mm), and Candia albicans (6.66±32 mm). Minimum inhibitory concentrations (MICs) were observed for MeOH extract between 3.12 to 25 mg/mL against S. pneumoniae, S. pyogens and Candida albicans respectively. The antimicrobial activity of the crude extracts of plant represents a significant outcome for the treatment of respiratory diseases.  


Keywords: Respiratory tract pathogens, antibacterial, antifungal,MIC,Barleria prionitis
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How to cite this article:

Ajeet Singh, Vinay Mohan Pathak and Navneet. 2016. Screening of Antimicrobial Potential of Barleria prionitis Linn Aerial Parts against Common Respiratory Tract PathogensInt.J.Curr.Microbiol.App.Sci. 5(7): 542-549. doi: http://dx.doi.org/10.20546/ijcmas.2016.507.059