National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Mitochondria is the key organelle of cell which provide energy output for various functions and mechanisms inside the cell with the production of ATP and it is directly linked to the protection from chronic diseases such as neurodegenerative diseases, heart disease, diabetes and metabolic syndrome. Its biogenesis get affected by the alterations in both nuclear and mitochondrial DNA (mtDNA) due to the improper oxidative phosphorylation process. One possible approach to relieve this deficiency might be to boost the residual OXPHOS capacity by increasing the mitochondrial functional mass in the affected tissues. Heart is the organ which continuously contract and pump blood to whole body and this contraction is maintained by energy output from mitochondria. So the biogenesis and mechanisms of mitochondria is directly proportional to the working capacity and quality of heart health. Current treatments for heart disease address the symptoms of deficiency but not the cure. One possible approach to relieve the deficiency might be to boost the residual OXPHOS capacity by increasing the mitochondrial functional mass in the affected tissues which leads to the proper biogenesis of mitochondria and heart function.
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