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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 3105-3110
DOI: https://doi.org/10.20546/ijcmas.2018.702.373


Evaluation of Reactivity Profile of Non-Structural Protein C of Peste-Des-Petits-Ruminnats Virus
Bhadouriya Sakshi1, Dheeraj Choudhary1, Ajay Yadav1,Chandra Sekar1, V.V. Dhanesh1, M. Sankar1, Kaushal K. Rajak2,R.P. Singh2, M.A. Ramakrishnan1 and Dhanavelu Muthuchelvan1*
1Division of Virology, ICAR-Indian Veterinary Research Institute, Mukteswar, Nainital District, Uttarakhand 263 138, India
2ICAR-Indian Veterinary Research Institute, Mukteswar, Nainital District,Uttarakhand 263 138, India
*Corresponding author
Abstract:

Peste-des-petits ruminants (PPR) is an economically devastating viral disease of sheep and goats. In the present study, we have evaluated the reactivity profile of the recombinant non-structural protein C of PPR virus with vaccinated and convalescent goat sera in an indirect ELISA. The antibody against this protein is getting produced in both vaccinated as well as in convalescent animals. Further, we evaluated the antibody production kinetics in vaccinated goats and found that antibodies against this protein is getting produced from the 14th day of post-vaccination and persists till the 40th day of the study period. The data generated in this study will be useful for the development of DIVA vaccine and diagnostics against PPR.


Keywords: Peste-des-petits-ruminants, PPR, Non-structural protein C, PPRV, Antibody kinetics
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How to cite this article:

Bhadouriya Sakshi, Dheeraj Choudhary, Ajay Yadav, S. Chandra Sekar, V.V. Dhanesh, M. Sankar, Kaushal K. Rajak, R.P. Singh, M.A. Ramakrishnan and Dhanavelu Muthuchelvan. 2018. Evaluation of Reactivity Profile of Non-Structural Protein C of Peste-Des-Petits-Ruminnats VirusInt.J.Curr.Microbiol.App.Sci. 7(2): 3105-3110. doi: https://doi.org/10.20546/ijcmas.2018.702.373