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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 2506-2514
DOI: https://doi.org/10.20546/ijcmas.2018.702.305


Immuno Correction of Genital Herpes of Viral Infection Moderate and Severe Course Betaleikin
L.K. Smailova1,3*, A.M. Kurmanova1, G.Ðœ. Kurmanova2, R.R. Razumova3 and A.A. Eszhanova3
1Scientific Centre of Obstetrics, Gynecology and Perinatology of Ministry of Public health and Social Development of the Republic of Kazakhstan, Almaty
2Kazakh National Medicinal University, Republic of Kazakhstan, Almaty
3JSC, Astana Medical University, Republic of Kazakhstan, Astana
*Corresponding author
Abstract:

Genital herpes is an important public health disease and is the leading cause of genital ulcer disease worldwide. After primary infection, the virus establishes a life-long latency in the sensory ganglia and recrudescences may occur at an unpredictable rate. Recurrent labial and genital herpes infections represent the majority of clinical manifestations of HSV infections. In the present study, ambulatory cards of 108 women with moderate and severe HSV infection were analyzed. Average age of study women was 32.8 ± 5.7 years. Study results analysis has shown that clinical symptoms manifestation varied depending on disease remoteness and herpetic infection severity. In overwhelming majority of patients (55.5%), frequency of herpetic infection relapses was 3 to 5 times (on average 5.6 ± 3.4 times) per year. Relapse duration varied 6 to 14 days and was 10.4 ± 4.2 days on average. In patients with moderate and severe HSV-infection, manifested decrease of cytokines level is observed: FNOα, IL-1β, INFγ, IL-4.


Keywords: Genital herpes, Viral infection, Immuno Correction
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How to cite this article:

Smailova, L.K., A.M. Kurmanova, G.М. Kurmanova, R.R. Razumova and Eszhanova, A.A. 2018. Immuno Correction of Genital Herpes of Viral Infection Moderate and Severe Course Betaleikin.Int.J.Curr.Microbiol.App.Sci. 7(2): 2506-2514. doi: https://doi.org/10.20546/ijcmas.2018.702.305