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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 2332-2340
DOI: https://doi.org/10.20546/ijcmas.2018.702.283


Mycological Profile of Chronic Rhinosinusitis
V.A. Vipula1, G. Shobha Latha1*, S. Radha1 and R.S. Pushpa Kumari2
1Department of Microbiology
2Department of General Medicine, MNR Medical College and Hospital, Sangareddy, Telangana, India
*Corresponding author
Abstract:

Aim of the to assess the purpose of fungal rhinosinusitis at MNR Medical College & Hospital, Sangareddy, and to correlate histopathological findings with culture results for accurate clinical classification of the disease. 217 suspected patients were included in the study. The relevant clinical details of the patients including the co-morbidities in the medical records were examined. Samples like nasal swabs collected during nasal endoscopy under sterile conditions, Sinus washings, Allergic mucin, tissue biopsy from polyps & tissue biopsy taken from sinus mucosa during nasal surgery, were processed and examined by microbiology culture using recommended techniques. Slide culture was done to observe the microscopic morphology. Histopathological examination was done by H and E stain and PAS stain for classification. Out of 217 cases of rhinosinusitis, 37 samples showed fungal isolates in culture. Aspergillus flavus was the most common isolate (8.29%). Aspergillus fumigatus was the second most common isolate (5.99%). Candida albicans was isolated in one sample and candida species, other than albicans was isolated in one more sample. On the basis of the histopathological findings, the fungal isolates were grouped. Among the 37 patients with fungal rhinosinusitis 26 patients belonged to non-invasive type. They were mostly of allergic etiology. The organisms were mostly Aspergillus fumigatus and Aspergillus flavus. Isolates that cause fungal ball were not isolated. 11 isolates belonged to invasive group. Most of them were Aspergillus flavus causing chronic granulomatous fungal sinusitis Mycological profile of rhinosinusitis at MNR Medical College, Sangareddy was thus evaluated. Histopathological and microbiological findings reported 37cases of fungal rhinosinusitis among 217 suspected cases of rhinosinusitis.


Keywords: Aspergillus flavus, Chronic rhinosinusitis, Fungal rhinosinusitis, H and E stain
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How to cite this article:

Vipula, V.A., G. Shobha Latha, S. Radha and Pushpa Kumari, R.S. 2018. Mycological Profile of Chronic Rhinosinusitis.Int.J.Curr.Microbiol.App.Sci. 7(2): 2332-2340. doi: https://doi.org/10.20546/ijcmas.2018.702.283