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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 1857-1861
DOI: https://doi.org/10.20546/ijcmas.2018.702.223


Determination of Prevalence of Filariasis by Rapid Card Test in a Tertiary Care Centre of North India
Galhotra Shipra1*, Prasad Amber2, Goyal Kapil3, Sehgal Rakesh4,Y. Pant4 and P. Tripathi4
1Department of Microbiology in GGS Medical College, Faridkot, Punjab, India
2Department of Microbiology Ranchi Institute of Medical Sciences, Ranchi, Jharkhand, India
3Department of Virology in Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
4Department of Parasitology in Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
*Corresponding author
Abstract:

The prevalence of lymphatic filariasis caused by Wuchereria bancrofti is very high in certain geographical regions and it is one of the neglected tropical diseases targeted for global elimination. So, there is an urgent need for the detection of circulating filarial antigen by rapid immunoassay in Global Programme to Eliminate Lymphatic Filariasis (GPELF). This programme as a public health aspect focuses on mass drug delivery after community diagnosis. The Immunochromatographic card test (ICT) which does not detect early exposure to lymphatic filariasis (LF) but detects active infection is recommended test in current WHO guidelines. The mapping of LF by ICT card test in recent years has decreased the night mass blood surveys, time consuming preparations and examination of blood slides. This study investigated the use of rapid ICT test for the detection of filariasis. A total of 243 suspected cases of filariasis were tested by ICT and 38 were tested for thick blood film (TBF) examination. The positivity rate of filariasis was 8.6% by ICT card test and it was lower in females than males. None of the sample was positive by TBF. The ICT card test was positive in 5 cases which were negative by TBF. This study demonstrates that ICT card test because of its rapidity and simplicity justifies its use for the detection of filariasis. This test should be applied in field studies and would be helpful in GPELF.


Keywords: ICT, Lymphatic filiariasis, TBF, Wuchereria bancrofti
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How to cite this article:

Galhotra Shipra, Prasad Amber, Goyal Kapil, Sehgal Rakesh, Y. Pant and Tripathi, P. 2018. Determination of Prevalence of Filariasis by Rapid Card Test in a Tertiary Care Centre of North India.Int.J.Curr.Microbiol.App.Sci. 7(2): 1857-1861. doi: https://doi.org/10.20546/ijcmas.2018.702.223