National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary tract infections, caused by multidrug resistant uropathogenic Escherichia coli (UPEC) are alarmingly escalating. Widespread utilization of empirical antibiotics without performing anti-microbial susceptibility testing led to expanding resistance to different classes of antimicrobial agents generally prescribed among UPEC isolates in our country. Therefore, this study aims to detect the prevalence and the antibiotic susceptibility pattern of UPEC isolates, in Tanta University Hospitals, Egypt. A total of 200 urine samples were collected from July 2015 to August 2016. Urine count and culture were done. Antibiotic susceptibility testing was performed according to the clinical and laboratory standards institute guidelines (CLSI 2016).E. coli was the predominant isolate (53.85%) followed by Klebsiella spp. (17.58%), Candida spp (10.99%), Proteus spp. (6.04%) Coagulase negative Staphylococcus (3.85%) Enterococcus spp. (2.75%), Pseudomonas spp. (2.19%), Acinetobacter baumannii (1.65%), Enterobacter spp. (0.55%) and Serrate marascences (0.55%). The highest percentage of UPEC isolates were non susceptible to Ampicillin, Cefazolin (100%) for each, followed by Nalidixic acid (91.84%), Trimethoprim/sulfamethoxazole (87.9%), Norfloxacin (82.65%), beta-lactam inhibitors (81.3%), Ceftriaxone (79.60%), Cefotaxime (74.49%), Ceftazidime (64.3%), Gentamicin (26.53%), Amikacin (22.45%), Nitrofurantoin (21.4%) and Imipenem (20.41%). Therefore, physicians must follow antibiotic stewardship and change their treatment pattern based on performing antibiotic susceptibility testing.
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