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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(7): 206-209
DOI: http://dx.doi.org/10.20546/ijcmas.2016.507.021


Nitrofurantoin Susceptibility in Urinary Tract Infections (UTIs) in an Era of Drug Resistance
J.Mariraj, S. Sadiqa Begum*, S. Krishna and Qurath Saba
Department of Microbiology, Vijaynagar Institute of Medical Sciences,Ballari 583104, Karnataka, India
*Corresponding author
Abstract:

UTI are the most common bacterial infections that account for significant morbidity and health care cost world-wide. The most profound advance in the  management of UTIs has been the introduction of antimicrobial agents. An old drug Nitrofurantoin has increased as a solution to the ever increasing menace of antimicrobial resistance. In this study, we studied the susceptibility pattern of Nitrofurantoin to the common uropathogens. Study was conducted from January 2015 to December 2015 in VIMS hospital Ballari. All the urine isolates are subjected to susceptibility  for Nitrofurantoin and results were interrupted. Among 1372 urinary isolates, 86.7% of E.Coli, 89.9% of S.aureus, 92.3% of Enterobacter spp, 88.6% of Klebsiella spp, 90% of Enterococcus were susceptible to Nitrofurantoin. Overall Nitrofurantoin showed 89.3% of susceptibility and 10.7% of resistance in urinary isolates. In this study nitrofurantoin showed 89.3% of susceptibility to the most common urinary isolates. Nitrofurantoin should be considered as an acceptable treatment for uncomplicated UTIs and should be considered the first line treatment.


Keywords: Urinary tract infection(UTI), Nitrofurantoin, antimicrobial susceptibility pattern, uropathogens, antimicrobial resistance.
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How to cite this article:

Mariraj, J., S. Sadiqa Begum, S. Krishna and Qurath Saba. 2016. Nitrofurantoin Susceptibility in Urinary Tract Infections (UTIs) in an Era of Drug Resistance.Int.J.Curr.Microbiol.App.Sci. 5(7): 206-209. doi: http://dx.doi.org/10.20546/ijcmas.2016.507.021