National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Typhoid fever is a systemic infection caused by Salmonella enterica subspecies enterica serovar Typhi. A very similar but often less severe disease is caused by S. paratyphi A, B and sometimes C. Enteric fever is endemic in all parts of India. S. typhi and S. paratyphi A are the predominant types of Salmonella responsible of enteric fever in India. An antibiogram is the result of a laboratory testing for the sensitivity of an isolated bacterial strain to different antibiotics. A descriptive study was conducted at the Department of Microbiology, Sri Siddhartha Medical College and Research centre, Tumkur from January 2015 to December 2016. A total of 292 isolates were studied. Antibiotic sensitivity was observed on Muller –Hinton agar plates by Kirby-Bauer disc diffusion methods according to National Committee for Clinical Laboratory (NCCL) guidelines. The male to female ratio was 2.3: 1. More cases are reported among males compared to females probably as a result of increased exposure to infection. Antibiotic susceptibility/resistance profile is also found to be similar in these two agents. In the recent days a change towards increased isolation of S. paratyphi A has been observed in many places. This can be explained by two hypothesis: 1. Increased vaccination against Typhoid fever and 2. Increased interest among the microbiologists. Both S. typhi and S. paratyphi A has similar distribution rate (54% and 46%). Present study represents amoxycillin and clavulinic acid, ceftriaxone, cefotaxime and amikacin are the drug of choice for typhoid fever.
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