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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 658-662
DOI: https://doi.org/10.20546/ijcmas.2018.702.081


A Study of Antibiotic Susceptibility Pattern of Salmonella typhi and Salmonella paratyphi A
S.C. Chandrashekar* and M. Sudeep Kumar
Sri Siddhartha Medical College and Research Centre, B H road, Agalakote, Tumkur – 572107, Karnataka, India
*Corresponding author
Abstract:

Typhoid fever is a systemic infection caused by Salmonella enterica subspecies enterica serovar Typhi. A very similar but often less severe disease is caused by S. paratyphi A, B and sometimes C. Enteric fever is endemic in all parts of India. S. typhi and S. paratyphi A are the predominant types of Salmonella responsible of enteric fever in India. An antibiogram is the result of a laboratory testing for the sensitivity of an isolated bacterial strain to different antibiotics. A descriptive study was conducted at the Department of Microbiology, Sri Siddhartha Medical College and Research centre, Tumkur from January 2015 to December 2016. A total of 292 isolates were studied. Antibiotic sensitivity was observed on Muller –Hinton agar plates by Kirby-Bauer disc diffusion methods according to National Committee for Clinical Laboratory (NCCL) guidelines. The male to female ratio was 2.3: 1. More cases are reported among males compared to females probably as a result of increased exposure to infection. Antibiotic susceptibility/resistance profile is also found to be similar in these two agents. In the recent days a change towards increased isolation of S. paratyphi A has been observed in many places. This can be explained by two hypothesis: 1. Increased vaccination against Typhoid fever and 2. Increased interest among the microbiologists. Both S. typhi and S. paratyphi A has similar distribution rate (54% and 46%). Present study represents amoxycillin and clavulinic acid, ceftriaxone, cefotaxime and amikacin are the drug of choice for typhoid fever.


Keywords: Salmonella typhi, Salmonella paratyphi A, Susceptibility, Antibiogram, Enteric fever
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How to cite this article:

Chandrashekar, S.C. and Sudeep Kumar, M. 2018. A Study of Antibiotic Susceptibility Pattern of Salmonella typhi and Salmonella paratyphi AInt.J.Curr.Microbiol.App.Sci. 7(2): 658-662. doi: https://doi.org/10.20546/ijcmas.2018.702.081