National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
HSV-1 also known as Oral herpes causes sores or lesions in the gums or near the mouth. Dry stem of Tinospora cordifolia is powdered and extraction is carried out in soxhlet apparatus using the solvent Methanol and Ethyl Acetate in the ratio 80:20. The crude extract was subjected to prelimnary phytochemical analysis which indicated the presence of Saponins, alkaloids, phytosterols and triterpenoids. The preparation of virus pool was carried out using Vero cell lines. MTT assay was conducted and the cytotoxicity level of T.corfiolia on the cells was obtained as 315.68±7.8. Viral titration was carried out followed by Virucidal assay and it was concluded that T.cordifolia inhibits the growth of HSV by 61.43% at 10TCID50.
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