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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(1): 2108-2116
DOI: https://doi.org/10.20546/ijcmas.2018.701.254


In vitro Assessment of Antibiotic Resistance Pattern among Lactobacillus Strains Isolated from Goat Milk
Nishchal Thakur, Chetan Sharma, Namita Rokana, Brij Pal Singh,Rohini Devidas Gulhane, Santosh Kumar Mishra, Sunil Kumar Khatkar,Anil Kumar Puniya and Harsh Panwar*
Department of Dairy Microbiology, College of Dairy Science and Technology, Guru Angad Dev Veterinary and Animal Sciences University (GADVASU), Ludhiana, Punjab, India
*Corresponding author
Abstract:

This study aimed to assess the antibiotic susceptibility of Lactobacillus strains of goat milk origin. Lactobacilli are generally recognized as safe, but can act as reservoir for genes carrying antibiotic resistance traits; which can further spread to commensal, food spoilage or pathogenic organisms. Lactic acid bacteria (LAB) strains coming from animal sources had significant interaction with antibiotics. Goat milk, being second to cow milk in production and due to its close resemblance to human milk composition, is among favorable source for isolating potential probiotic LAB strains. Herein, this study assessed the antibiotic susceptibility pattern of fourteen Lactobacillus strains isolated from goat milk. The antibiotic susceptibility was recorded against thirty antibiotics following standard disk-diffusion assay. Imipenem, meropenem and nitrofurantoin turned out to be the most effective antibiotics, displaying high zone of inhibition (ZOI) against all the isolates. In contrast, all lactobacilli strains exhibited resistance pattern towards methicillin, oxacillin, cefoxitin, cefmetazole, teicoplanin, vancomycin, ciprofloxacin, ofloxacin, streptomycin, tobramycin, clindamycin and fusidic acid group antibiotics. Overall, GM4 (L. plantarum) displayed highest resistance with clear resistance phenotype against 18/30 antibiotics tested and intermediate resistance against other 5 antibiotics. This study generates new data pertaining to the antibiotic resistance risk of new candidate probiotic strains from goat milk.


Keywords: Lactobacillus, Goat milk, Susceptibility, Resistance, Probiotics
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How to cite this article:

Nishchal Thakur, Chetan Sharma, Namita Rokana, Brij Pal Singh, Rohini Devidas Gulhane, Santosh Kumar Mishra, Sunil Kumar Khatkar, Anil Kumar Puniya and Harsh Panwar. 2018. In vitro Assessment of Antibiotic Resistance Pattern among Lactobacillus Strains Isolated from Goat Milk.Int.J.Curr.Microbiol.App.Sci. 7(1): 2108-2116. doi: https://doi.org/10.20546/ijcmas.2018.701.254