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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(1): 1244-1252
DOI: https://doi.org/10.20546/ijcmas.2018.701.151


Phenotypic Screening for Asymptomatic Rectal Colonization by Resistant Enterobacteriaceae and Nasal MRSA Colonization in Critical Care Patients
Sujatha K. Karjigi* and Saroj Golia
Department of Microbiology, Dr. B.R. Ambedkar Medical College, KG halli, Bangalore, Karnataka, India
*Corresponding author
Abstract:

Critical care populations are at high risk for Multi drug resistant organisms (MDRO) colonization because of rampant use of broad-spectrum antibiotics leading to colonization with resistant strains, Screening for MDR organisms is one of the many approaches needed to deal with the very major clinical problem concerning drug resistance. This study was planned to look for antibiotic resistance by simple phenotypic methods to detect Resistant Enterobacteriaceae include broad spectrum β-lactamase producing Enterobacteriaceae (ESBL and AmpC β-lactamases) and carbapenem-resistant Enterobacteriaceae (CRE)and or combinations of any in one go and nasal screening for Methicillin Resistant Staphylococcus Aureus (MRSA). Total of 110 patients admitted intensive care unit were screened by taking rectal and nasal swab over period of year. In our study 234-gram negative bacilli were isolated from 110 rectal swabs among those were 54(23.7%) ESBL, 22(9.4%) Amp C, and 30 (12.8%) isolates were carbapenem resistant which includes 21(8.9%) isolates were cabapenemase producer by MHT and MBL screen and 9(2.64%) isolates were carbapenemase +Amp C+ESBL combined producers. Nasal MRSA carriage rate was 8%. Present study emphasis the need for strong infection control programs to detect colonization of gut and other anatomical site by multidrug resistant organisms. Need to reduce overuse of antibiotics and establish good antibiotic stewardship programs and implementation of screening in intensive care unit.


Keywords: Critical care, Colonization, Screening, Antibiotic resistance, ESBL, MBL
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How to cite this article:

Sujatha K. Karjigi and Saroj Golia. 2018. Phenotypic Screening for Asymptomatic Rectal Colonization by Resistant Enterobacteriaceae and Nasal MRSA Colonization in Critical Care Patients.Int.J.Curr.Microbiol.App.Sci. 7(1): 1244-1252. doi: https://doi.org/10.20546/ijcmas.2018.701.151