National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Critical care populations are at high risk for Multi drug resistant organisms (MDRO) colonization because of rampant use of broad-spectrum antibiotics leading to colonization with resistant strains, Screening for MDR organisms is one of the many approaches needed to deal with the very major clinical problem concerning drug resistance. This study was planned to look for antibiotic resistance by simple phenotypic methods to detect Resistant Enterobacteriaceae include broad spectrum β-lactamase producing Enterobacteriaceae (ESBL and AmpC β-lactamases) and carbapenem-resistant Enterobacteriaceae (CRE)and or combinations of any in one go and nasal screening for Methicillin Resistant Staphylococcus Aureus (MRSA). Total of 110 patients admitted intensive care unit were screened by taking rectal and nasal swab over period of year. In our study 234-gram negative bacilli were isolated from 110 rectal swabs among those were 54(23.7%) ESBL, 22(9.4%) Amp C, and 30 (12.8%) isolates were carbapenem resistant which includes 21(8.9%) isolates were cabapenemase producer by MHT and MBL screen and 9(2.64%) isolates were carbapenemase +Amp C+ESBL combined producers. Nasal MRSA carriage rate was 8%. Present study emphasis the need for strong infection control programs to detect colonization of gut and other anatomical site by multidrug resistant organisms. Need to reduce overuse of antibiotics and establish good antibiotic stewardship programs and implementation of screening in intensive care unit.
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