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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Carbapenamases producing Klebsiella pneumoniae subspp pneumoniae strains are increasing worldwide and pose a major threat to patient care. Hence, the present study was undertaken to detect the incidence of Carbapenamases producing Klebsiella pneumoniae subspp pneumoniae strains isolated from different clinical specimens in the department of Microbiology and Antibiotic Susceptibility profile of Klebsiella pneumoniae subspecies pneumoniae strains. The study was approved by Institutional Ethical Committee (IEC). The type of study was cross sectional observational study. 300 Klebsiella pneumoniae subspp pneumoniae strains were studied. Antibiotic susceptibility test was done by Kirby-Bauer disc diffusion method. In our present study, 29.3% strains were CRKP. Out of total 300 Klebsiella pneumoniae subspp pneumoniae strains, 83 (27.7%), 90 (30%), 56 (18.7%), 40 (13.3%) and 96 (32%) were positive by Classical Hodge test, Modified Hodge test, MBL confirmatory test, KPC confirmatory test and Carbapenem hydrolysis positive due to MBL and KPC production respectively. In the present study (19/300 i.e.6.3%) Klebsiella pneumonia strains were MBL and KPC Co- producers. 13.3% KPC, 18.7% Klebsiella pneumoniae strains were MBL producing Klebsiella pneumoniae strains were isolated. All 300 Klebsiella pneumoniae strains studied were sensitive to colistin (100%), followed by Imipenem (70.6%). All Klebsiella pneumoniae subspp pneumoniae strains, isolated in Clinical Microbiology Laboratory should be tested phenotypically for Carbapenamases production.