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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(1): 289-294
DOI: https://doi.org/10.20546/ijcmas.2018.701.031


Antimicrobial Susceptibility Pattern of Escherichia coli from Patients with Urinary Tract Infections in a Tertiary Care Hospital
B. Shanthi, R. Selvi* and A. Madhumathy
Department of Microbiology, Stanley Medical College, Chennai – 01, Tamil Nadu, India
*Corresponding author
Abstract:

Urinary tract infection (UTI) is one of the most common bacterial infections in humans after respiratory tract infection. E.coli remains the leading uropathogen being responsible for UTI. The aim of the study is to assess the resistance pattern of E.coli causing UTI to commonly used antibiotics, so as to aid the clinician in changing the appropriate antimicrobial empirical therapy. E.coli isolated from urine samples were identified by conventional biochemical test. Antimicrobial susceptibility test was done by Kirby–Bauer disc diffusion method on Mueller–Hinton agar. Among the 2101 isolates, E.coli was the most common pathogen. Majority of the isolates showed high resistance to gentamycin (37.39%), cotrimoxazole (24.20%), ciprofloxacin (26.05%), norfloxacin (27.29%) and cefotaxime (21.73%), and least resistance to Nitrofurantoin (85.89%) and Amikacin (68.89%). Antibiotics such as gentamycin, cotrimoxazole, ciprofloxacin, norfloxcin and cefotaxime have limited value for the treatment of UTI. Nitrofurantoin and Amikacin should be used in empirical therapy of UTI.


Keywords: Urinary tract infections, E. coli, Antibiotic sensitivity
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How to cite this article:

Shanthi, B., R. Selvi and Madhumathy, A. 2018. Antimicrobial Susceptibility Pattern of Escherichia coli from Patients with Urinary Tract Infections in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 7(1): 289-294. doi: https://doi.org/10.20546/ijcmas.2018.701.031