National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
To study the Histopathological changes and tissue residue deposition in broiler birds following profenofos administration. Twenty birds were divided into two groups, 10 in each group. Group I served as control and group II was treated with single oral dose of Profenofos (16 mg/kg). Representative pieces of tissues from liver, kidney, lung, brain and muscle were collected for histopathological examination and residue estimation. Birds treated with profenofos showed marked histopathological changes. Cellular swelling, coagulative necrosis, hydropic degeneration and congestion were observed in most of the tissue examined. The brain section revealed neuronophagia and setellosis. The concentration of profenofos residues ranged from 0.02 to 0.05 ug/g in tested tissues. The level of residue in tissue was found to be maximum in brain while least was observed in muscle. Profenofos administration at the dose of 16 mg/kg cause considerable histopathological changes and little tissue residue deposition.
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