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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(12): 3040-3048
DOI: https://doi.org/10.20546/ijcmas.2017.612.355


Neonatal Sepsis: Antibiotic Sensitivity and Resistance Pattern of Most Common Isolated Pathogens in a Neonatal Intensive Care Unit of a Tertiary Care Hospital
Mayuri Bhise, Prakash Waghmare*, Sapana Mundhada, Anu Sharma and Kishor Ingole
Department of Microbiology, Dr.V.M. Government medical college Solapur, Maharashtra, India
*Corresponding author
Abstract:

Septicemia in neonates refers to generalized bacterial infection documented by positive blood culture in the first four weeks of life. Neonatal sepsis is one of the commonest causes of neonatal mortality in the developing world. To isolate and identify the bacterial isolates responsible for neonatal sepsis. Objective of the study is to determine the susceptibility pattern of isolates. 80 blood samples were collected and processed from patients in accordance with standard protocols. Identification of organisms, the antibiotic susceptibility of the isolates and Methicillin resistant Staphylococcus aureus (MRSA) and ESBL detection was done by Kirby Bauer disc diffusion method according to National Committee for Clinical Laboratory Standards (NCCLS) recommendations. Among the culture positive specimens, Klebsiella pneumoniae was the most commonly isolated pathogen followed by Escherichia coli and overall Gram negative organisms were isolated predominantly than gram positive organisms Gram negative bacteria also exhibited high resistance to the commonly prescribed group of drugs such as penicillins and cephalosporins, Klebsiella pneumoniae and MRSA were the commonly isolated gram negative and gram positive organism respectively.


Keywords: Neonatal septicemia, Blood culture, Antibiotic Susceptibility Pattern, Extended Spectrum β-Lactamases (ESBL), Methicillin Resistant Staphylococcus aureus (MRSA).
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How to cite this article:

Mayuri Bhise, Prakash Waghmare, Sapana Mundhada, Anu Sharma and Kishor Ingole. 2017. Neonatal Sepsis: Antibiotic Sensitivity and Resistance Pattern of Most Common Isolated Pathogens in a Neonatal Intensive Care Unit of a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(12): 3040-3048. doi: https://doi.org/10.20546/ijcmas.2017.612.355