Haematocarpus validus (Miers.) Bakh. f. ex Forman is a woody perennial climber belonging to the family of Menispermaceae and found in the hot and humid tropics of Asian continent. It is a lesser known and rare ethnic fruit crop of high nutraceutical and traditional medicinal value with hepatoprotective and anti-inflammatory properties. There is no report on the secondary metabolites present in this plant and this is the first report on various alkaloids present in the leaf and fruit samples of this ethnomedicinal plant. In the present communication, we report six alkaloid compounds viz., Ecgonine (leaf); Sinomenine (leaf); Metanephrine (fruit), Reticuline (fruit), Ambelline (fruit), and choline (in both leaf and fruit) detected through HR LCMS analysis.

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